The sequences of proteins encoded by HLA genes were downloaded from the IMGT/HLA database (https://www.ebi.ac.uk/ipd/imgt/hla), and the residue numbers of all obtained protein sequences were re-numbered to correspond to those in the HLA-A*0201 allele (1A07). The peptide-binding environment for each HLA molecule encoded by HLA-A and -B genes was collected according to the definition of Nielsen# and stored in a database of HLA peptide-binding fingerprints embedded in PromPDD.

 

 

Search for alleles with the identical binding specificity
Input the protein name encoded by a specific HLA allele		example: "A*02:01, B*07:02"

 

 

 

    #Nielsen M, Lundegaard C, Blicher T, Lamberth K, Harndahl M, Justesen S, Roder G, Peters B, Sette A, Lund O et al: NetMHCpan, a method for quantitative predictions of peptide binding to any HLA-A and -B locus protein of known sequence. PLoS One 2007, 2(8):e796.

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