HLA Class I supertypes and alleles available in this website
|
| A1 |
A2 |
A3 |
A24 |
A01A03 |
A01A24 |
B7 |
B44 |
B58 |
B27 |
B62 |
B08 |
unclassified |
| A*0101 |
A*0201 |
A*0301 |
A*2301 |
A*3001 |
A*2902 |
B*0702 |
B*1801 |
B*5701 |
B*2704 |
B*1501 |
B*0801 |
B*4901 |
| A*2601 |
A*0202 |
A*1101 |
A*2402 |
|
|
B*3501 |
B*4001 |
B*5801 |
B*2705 |
|
|
|
| A*3002 |
A*0203 |
A*3101 |
A*2403 |
|
|
B*5101 |
B*4002 |
|
B*2706 |
|
|
|
| |
A*0206 |
A*3301 |
|
|
|
B*5301 |
B*4402 |
|
B*2709 |
|
|
|
| |
A*6802 |
A*6801 |
|
|
|
B*5401 |
B*4403 |
|
B*3901 |
|
|
|
| |
|
|
|
|
|
|
B*4501 |
|
|
|
|
|
Ref: Sidney J, Peters B, Frahm N, Brander C, Sette A. HLA class I supertypes: a revised and updated classification. BMC Immunol. 2008 Jan 22;9:1 |
|
The super-motifs of HLA class I supertypes
|
| Supertype |
Super-motif |
| |
Position 2 |
C-terminus |
| A1 |
TILVMS |
FWY |
| A2 |
AILMVT |
AILMVT |
| A3 |
AILMVST |
KRY |
| A24 |
YFWIVLMT |
FIYWLM |
| B7 |
P |
AILMVFWY |
| B44 |
ED |
FWYLIMVA |
| B27 |
RHK |
FYLWMI |
| B62 |
QLIVMP |
FWYMIV |
| B58 |
ATS |
FWYLIV |
Ref: Sette A, Sidney J. Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism. Immunogenetics, 1999, 50: 201-212 |
|
Threshold
|
The Threshold for each allele were modified the optimized cutoff value and the value was set to 1.
Peptides with big values mean high potential to bind to the corresponding HLA molecule.
|
